diff --git a/Kbuild b/Kbuild
index 2c3af0807975..0a99d9c985e8 100644
--- a/Kbuild
+++ b/Kbuild
@@ -2603,6 +2603,7 @@ cppflags-$(CONFIG_WLAN_FEATURE_ELNA) += -DWLAN_FEATURE_ELNA
 cppflags-$(CONFIG_FEATURE_COEX) += -DFEATURE_COEX
 cppflags-$(CONFIG_CM_ROAM_OFFLOAD) += -DROAM_OFFLOAD_V1
 cppflags-$(CONFIG_INTERFACE_MGR) += -DWLAN_FEATURE_INTERFACE_MGR
+cppflags-$(CONFIG_HOST_WAKEUP_OVER_QMI) += -DHOST_WAKEUP_OVER_QMI
 
 cppflags-$(CONFIG_PLD_IPCI_ICNSS_FLAG) += -DCONFIG_PLD_IPCI_ICNSS
 cppflags-$(CONFIG_PLD_SDIO_CNSS_FLAG) += -DCONFIG_PLD_SDIO_CNSS
diff --git a/configs/default_defconfig b/configs/default_defconfig
index d5bab23093bf..83182d80a713 100644
--- a/configs/default_defconfig
+++ b/configs/default_defconfig
@@ -64,6 +64,7 @@ ifeq ($(CONFIG_CNSS_QCA6750), y)
 	CONFIG_SCALE_INCLUDES := y
 	CONFIG_HASTINGS_BT_WAR := y
 	CONFIG_WDI3_IPA_OVER_GSI :=y
+	CONFIG_HOST_WAKEUP_OVER_QMI := y
 endif
 
 ifeq ($(CONFIG_CLD_HL_SDIO_CORE), y)