diff --git a/drivers/gpio/gpio-pca953x.c b/drivers/gpio/gpio-pca953x.c
index c81d73d5e015..37c209a83ecd 100644
--- a/drivers/gpio/gpio-pca953x.c
+++ b/drivers/gpio/gpio-pca953x.c
@@ -1199,6 +1199,9 @@ static int pca953x_suspend(struct device *dev)
 	struct pca953x_chip *chip = dev_get_drvdata(dev);
 
 	mutex_lock(&chip->i2c_lock);
+	/* Disable IRQ to prevent early triggering while regmap "cache only" is on */
+	if (chip->client->irq > 0)
+		disable_irq(chip->client->irq);
 	regcache_cache_only(chip->regmap, true);
 	mutex_unlock(&chip->i2c_lock);
 
@@ -1224,6 +1227,8 @@ static int pca953x_resume(struct device *dev)
 	}
 
 	mutex_lock(&chip->i2c_lock);
+	if (chip->client->irq > 0)
+		enable_irq(chip->client->irq);
 	regcache_cache_only(chip->regmap, false);
 	regcache_mark_dirty(chip->regmap);
 	ret = pca953x_regcache_sync(dev);